Human-wildlife conflict is increasingly common around the world, and the consequences of these interactions can be profound. Large carnivores in particular can exert significant economic and social costs by killing livestock, and they may even pose a direct threat to human life. Consequently, attempts to reduce conflicts with carnivores primarily occur through landscape-scale exclusion and lethal control. While it is recognized that ongoing lethal control can be economically, ecologically and culturally costly, most stakeholders perceive few alternatives. Barring a few effective examples of non-lethal conflict prevention tools, such as livestock guardian animals, there is little to suggest otherwise. Arguably however, a major source of potential non-lethal human-wildlife conflict solutions is yet to be fully explored and applied. Although biomimicry - taking inspiration from nature to solve key human problems - has been applied to solve a diverse number of humanity’s grand challenges from bird-inspired aviation to swimsuits modelled on properties of shark skin, nature has inspired very few human-wildlife conflict solutions. Focusing on potential tools based on animal signals, I will describe my ongoing biomimetic approach to reduce human-wildlife conflict. I’ll explore the potential and complexity of developing “scent-fences” for African wild dogs and dingoes, and acoustic visual deterrents for lions and other ambush predators. While we become increasingly confident that complex technologies will get us out of all kinds of trouble, is it possible that many of our major conservation challenges already have naturally-selected solutions?